Home Current issue Ahead of print Search About us Editorial board Archives Submit article Instructions Subscribe Contacts Login 
Year : 2016  |  Volume : 35  |  Issue : 2  |  Page : 106-111

Predictive value of axillary nodal mapping after neoadjuvant chemotherapy in breast cancer

1 Department of Surgery, Menofia University, Menofia, Egypt
2 Department of Pathology, Cairo University, Cairo, Egypt
3 Department of Surgery, National Cancer Institute (NCI), Cairo University, Cairo, Egypt
4 Department of Radiation Oncology, National Cancer Institute (NCI), Cairo University, Cairo, Egypt
5 Department of Medical Oncology, National Cancer Institute (NCI), Cairo University, Cairo, Egypt

Correspondence Address:
Hossam Abdel Kader El Fol
MD, General Surgery Department, Menofia University Hospital, Shebin El-Kom
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1110-1121.182784

Rights and Permissions

Purpose The aim of the study was to determine the feasibility and accuracy of sentinel lymph node biopsy (SLNB) in patients with advanced breast cancer after preoperative chemotherapy. Patients and methods A prospective study was conducted on 73 patients with advanced operable breast carcinoma previously treated with preoperative chemotherapy. Sentinel lymph node (SLN) mapping was performed at the time of surgery. Following surgery all patients received comprehensive postoperative radiotherapy at 50 Gy/5 weeks. Results Seventy-three patients with a median age of 52 years who had been previously treated with preoperative chemotherapy at Menofia University Hospital and National Cancer Institute (NCI) between May 2006 and May 2013 were selected for this study. The SLN detection rate was 79.5%. Thirty-three of 58 patients (56.9%) had successfully mapped positive SLNs. The false-negative rate was 22.4%. Conclusion This study confirms the feasibility of SLNB after preoperative chemotherapy in the case of advanced operable breast cancer. According to the detection rate and false-negative rate SLNB may predict metastatic disease in the axilla of patients with tumor response following preoperative chemotherapy.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded111    
    Comments [Add]    

Recommend this journal